Article
Cytochrome P450 1B1 gene polymorphisms and postmenopausal breast cancer risk.
Carcinogenesis - 1 Sept 2003
Rylander-Rudqvist Tove, Wedren Sara, Granath Fredrik, Humphreys Keith, Ahlberg Susanne, Weiderpass Elisabete, Oscarson Mikael, Ingelman-Sundberg Magnus, Persson Ingemar
Abstract excerpt
Cytochrome P450 1B1 (CYP1B1) is active in the metabolism of estrogens to reactive catechols and of different procarcinogens. Several studies have investigated the relationship between genetic polymorphisms of CYP1B1 and breast cancer risk, however, with inconsistent results. We investigated such...
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