Article
CYP1B1 and predisposition to breast cancer in Poland.
Breast cancer research and treatment - 1 Dec 2007
Matyjasik Joanna, Cybulski Cezary, Masojć Bartlomiej, Jakubowska Anna, Serrano-Fernandez Pablo, Górski Bohdan, Debniak Tadeusz, Huzarski Tomasz, Byrski Tomasz, Gronwald Jacek, Złowocka Elzbieta, Narod Steven Alexander, Scott Rodney, Lubinski Jan
Abstract excerpt
BACKGROUND: The CYP1B1 gene is a polymorphic member of the P450 gene family and is considered to be a candidate gene for cancers of various types. OBJECTIVE: We inquired whether four SNPs in the CYP1B1 gene, alone or in combination, might be associated with breast cancer risk in Poland. METHODS: We genotyped 2017 cases of breast cancer and 876 controls, for four SNPs in the CYP1B1 gene. Genotype and haplotype...
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