Article
Functional variant rs10175368 which affects the expression of CYP1B1 plays a protective role against breast cancer in a Chinese Han population.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Sept 2023
Liu Jiarui, Zhang Lijia, Tang Mingwen, Chen Xinyu, Yang Caiyun, Li Yong, Feng Jin, Deng Yan, Wang Xin, Zhang Yi
Abstract excerpt
OBJECTIVE: Cytochrome P450 1B1 ( CYP1B1 ) genetic variants are relevant in the pathogenesis of breast cancer. Exploring the relationships between CYP1B1 functional variants and breast cancer could improve our understanding of breast cancer molecular pathophysiology. METHODS: This is a two-stage hospital-based case-control study of a Chinese Han population. Genotyping was performed to identify candidate gene...
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