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Article

Analysis of TNFAIP3, IRAK1, and TLR4 Gene Polymorphisms in Patients With Rheumatoid Arthritis.

Immunity, inflammation and disease - 1 Feb 2026

Tang Zhenboyang, Peng Lihui, Zhao Zixia, Zhou Xiping, Ling Xiru, Huang Chunyan, Wu Jiqiang, Wang Ping, Chen Jie

Abstract excerpt

OBJECTIVE: Rheumatoid arthritis (RA) arises from a complex interplay of polygenic susceptibility, epigenetic factors, and environmental modifiers. This study investigated the correlation between RA and Tumor necrosis factor α-induced protein 3 (TNFAIP3), Interleukin-1 receptor-associated kinase 1 (IRAK1), and Toll-like receptor 4 (TLR4) gene polymorphisms. METHODS: A sample of 308 RA cases and 310 matched...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41684094
DOI: 10.1002/iid3.70344
PMCID: PMC12902183

Genes

TNFAIP3
IRAK1
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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