Article
Functional evaluation of TNFAIP3 (A20) in rheumatoid arthritis.
Clinical and experimental rheumatology - 1 Jan 2000
Elsby L M, Orozco G, Denton J, Worthington J, Ray D W, Donn R P
Abstract excerpt
OBJECTIVES: To determine the protein expression of TNFAIP3 in synovium and to show the capability of 6q23 intergenic SNPs, associated with rheumatoid arthritis (RA) susceptibility, to influence TNFAIP3 gene transcription. METHODS: Immunohistochemistry for TNFAIP3, NF-kB p65 and phosphorylated NF-kB p65 protein expression was performed in 6 RA knee joint synovium samples compared to 9 osteoarthritis (OA) samples....
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