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Article

Kinetics of CHO A L mutant expression after treatment with gamma radiation, EMS, and asbestos.

Cytometry. Part A : the journal of the International Society for Analytical Cytology - 1 May 2009

Keysar Stephen B, Fox Michael H

Abstract excerpt

The flow cytometry mutation assay (FCMA) uses hybrid CHO A(L) cells to measure mutations of the cd59 gene located on human chromosome 11 by the absence of fluorochrome-conjugated antibody binding to the CD59 surface antigen. Mutant expression peaks between 6 and 12 days, then decreases to a stable plateau, instead of a constant mutant fraction obtained by clonogenic assays. To evaluate this variable mutant...

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Identifiers

PMID: 19291804
DOI: 10.1002/cyto.a.20708
PMCID: PMC2700661

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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