Article
Mutant spectra of irradiated CHO AL cells determined with multiple markers analyzed by flow cytometry.
Mutation research - 1 Nov 2007
Ross Carley D, French C Tenley, Keysar Stephen B, Fox Michael H
Abstract excerpt
We have previously developed a sensitive and rapid mammalian cell mutation assay which is based on a Chinese hamster ovary cell line that stably incorporates human chromosome 11 (CHO A(L)) and uses flow cytometry to measure mutations in CD59. We now show that multiparameter flow cytometry may be used to simultaneously analyze irradiated CHO A(L) cells for mutations in five CD genes along chromosome 11 (CD59,...
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