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Article

Flow cytometric detection of tandem repeat mutations induced by various chemical classes.

Mutation research - 25 Jun 2006

Healy Caroline, Wade Mike, McMahon Avril, Williams Andrew, Johnson Douglas A, Parfett Craig

Abstract excerpt

To facilitate detection of genotoxicity from environmental mutagen exposure, we generated an in vitro enhanced green fluorescence protein (EGFP) reactivation assay that quickly and effectively detects frameshift mutations in tandem repeat sequences (TRS). Two murine cell lines, C3H10T1/2 and mismatch repair deficient MC2a, were stably transfected with EGFP reporter plasmids in which the EGFP constructs contain...

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Identifiers

PMID: 16516933
DOI: 10.1016/j.mrfmmm.2006.01.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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