Article
Missing call bias in high-throughput genotyping.
BMC genomics - 13 Mar 2009
Fu Wenqing, Wang Yi, Wang Ying, Li Rui, Lin Rong, Jin Li
Abstract excerpt
BACKGROUND: The advent of high-throughput and cost-effective genotyping platforms made genome-wide association (GWA) studies a reality. While the primary focus has been invested upon the improvement of reducing genotyping error, the problems associated with missing calls are largely overlooked. RESULTS: To probe into the effect of missing calls on GWAs, we demonstrated experimentally the prevalence and severity...
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