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Article

Genotyping and inflated type I error rate in genome-wide association case/control studies.

BMC bioinformatics - 23 Feb 2009

Sampson Joshua N, Zhao Hongyu

Abstract excerpt

BACKGROUND: One common goal of a case/control genome wide association study (GWAS) is to find SNPs associated with a disease. Traditionally, the first step in such studies is to assign a genotype to each SNP in each subject, based on a statistic summarizing fluorescence measurements. When the distributions of the summary statistics are not well separated by genotype, the act of genotype assignment can lead to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19236714
DOI: 10.1186/1471-2105-10-68
PMCID: PMC2679732

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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