Article
A TNF region haplotype offers protection from typhoid fever in Vietnamese patients.
Human genetics - 1 Aug 2007
Dunstan Sarah J, Nguyen Thi Hue, Rockett Kirk, Forton Julian, Morris Andrew P, Diakite Mahamadou, Mai Ngoc Lanh, Le Thi Phuong, House Deborah, Parry Christopher M, Ha Vinh, Nguyen T Hieu, Dougan Gordon, Tran Tinh Hien, Kwiatowski Dominic, Farrar Jeremy J
Abstract excerpt
The genomic region surrounding the TNF locus on human chromosome 6 has previously been associated with typhoid fever in Vietnam (Dunstan et al. in J Infect Dis 183:261-268, 2001). We used a haplotypic approach to understand this association further. Eighty single nucleotide polymorphisms (SNPs) s...
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