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Article

Human Genetic Variation Influences Enteric Fever Progression.

Cells - 6 Feb 2021

Ma Pei Yee, Tan Jing En, Hee Edd Wyn, Yong Dylan Wang Xi, Heng Yi Shuan, Low Wei Xiang, Wu Xun Hui, Cletus Christy, Kumar Chellappan Dinesh, Aung Kyan, Yong Chean Yeah, Liew Yun Khoon

Abstract excerpt

In the 21st century, enteric fever is still causing a significant number of mortalities, especially in high-risk regions of the world. Genetic studies involving the genome and transcriptome have revealed a broad set of candidate genetic polymorphisms associated with susceptibility to and the severity of enteric fever. This review attempted to explain and discuss the past and the most recent findings on human...

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PMID: 33562108
DOI: 10.3390/cells10020345
PMCID: PMC7915608

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