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Article

Genetic variants in IL-23R and ATG16L1 independently predispose to increased susceptibility to Crohn's disease in a Canadian population.

Journal of clinical gastroenterology - 1 Jan 2000

Newman William G, Zhang Qing, Liu Xiangdong, Amos Christopher I, Siminovitch Katherine A

Abstract excerpt

GOALS: To establish the relevance of variants in the IL-23R and ATG16L1 genes in inflammatory bowel disease (IBD). AIM: Three recent genome wide association studies have identified variants in the IL-23R and ATG16L1 genes, which modulate susceptibility to Crohn's disease (CD). METHODS: We genotyped 1028 IBD patients, including 443 CD and 347 ulcerative colitis (UC) non-Jewish cases, 238 (183 CD and 55 UC) Jewish...

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Identifiers

PMID: 19276991
DOI: 10.1097/MCG.0b013e318168bdf0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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