Article
Detection of EGFR mutations in non-small cell lung cancer by droplet digital PCR.
PloS one - 1 Jan 2022
Williamson Drew F K, Marris Sean R N, Rojas-Rudilla Vanesa, Bruce Jacqueline L, Paweletz Cloud P, Oxnard Geoffrey R, Sholl Lynette M, Dong Fei
Abstract excerpt
Activating mutations in EGFR predict benefit from tyrosine kinase inhibitor therapy for patients with advanced non-small cell lung cancer. Directing patients to appropriate therapy depends on accurate and timely EGFR assessment in the molecular pathology laboratory. This article describes the analytical design, performance characteristics, and clinical implementation of an assay for the rapid detection of EGFR...
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