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Article

Evaluation of molecular methods for plasma detection of EGFR mutations in non-small cell lung cancer.

Asia-Pacific journal of clinical oncology - 1 Dec 2022

Lee Kyunghoon, Lim Sangeun, Lee Yun-Gyoo, Kim Haejeung, Lee Seungjun, Yu Hui-Jin, Park Hyosoon, Kwon Min-Jung, Woo Hee-Yeon

Abstract excerpt

AIM: Epidermal growth factor receptor (EGFR) mutations are detected in non-small cell lung cancer (NSCLC) and associated with responses to therapy with tyrosine kinase inhibitors (TKIs). We compared the analytical performances of two real-time PCRs and droplet digital PCR (ddPCR) to detect EGFR mutations using plasma. METHODS: Plasma EGFR tests were performed using 86 plasma samples from 75 prospectively enrolled...

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PMID: 35098673
DOI: 10.1111/ajco.13705

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