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Article

Nucleotide composition of genes and hydrophobicity of the encoded proteins.

FEBS letters - 29 Jun 1992

Mázek J, Kypr J

Abstract excerpt

We find that true proteins are generally more hydrophobic than the corresponding hypothetical proteins encoded by the randomized gene nucleotide sequences. Furthermore, the protein hydrophobicity but not its gene nucleotide composition is conserved within evolutionary families of functionally related proteins. These two findings indicate that there is a general drift to modify gene nucleotide composition in the...

Topics

Adenosine
Animals
Base Composition
Biological Evolution
Codon
Fungi
Genes
Humans
Mutation
Protein Conformation
Proteins
Thymidine

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Identifiers

PMID: 1618344
DOI: 10.1016/0014-5793(92)80887-m

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1618344-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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