Article
Analysis of amino acid pairs sensitive to variants in human collagen alpha5(IV) chain precursor by means of a random approach.
Peptides - 1 Mar 2003
Wu Guang, Yan Shaomin
Abstract excerpt
In this data-based theoretical analysis, we use the random approach to analyze the amino acid pairs in 5(IV) chain precursor (CA54) in order to determine which amino acid pairs are more sensitive to 151 variants from missense mutant human CA54 protein. The rationale of this study is based on our hypothesis and previous findings that harmful variance is more likely to occur at randomly unpredictable amino acid...
Topics
- Amino Acids
- Collagen
- Computational Biology
- Genetic Variation
- Humans
