Article
[Mitochondrial D-Loop gene polymorphisms in the patients with type 2 diabetes mellitus].
Yi chuan = Hereditas - 1 Mar 2009
Chen Fang-Jian, Yu Hong, Fan Fan, Lu Jian-Xin
Abstract excerpt
Polymerase chain reaction (PCR) and direct nucleotide sequencing were used to analyze the mitochondrial D-loop gene of 199 Zhejiang patients with T2DM and 102 controls and the relationship between D-Loop gene variations and the main clinical symptoms. The mitochondrial D-Loop gene was a hypervariable area and np73A-G, np263A-G, np16223C-T, and np16519T-C were four high variations, and 29 unreported new variations...
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