Mitochondrial DNA mutations in diabetes mellitus patients in Chinese Han population.

doi:10.1016/j.gene.2013.09.019

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Article

Mitochondrial DNA mutations in diabetes mellitus patients in Chinese Han population.

Gene - 1 Dec 2013

Wang Suijun, Wu Songhua, Zheng Taishan, Yang Zhen, Ma Xiaojing, Jia Weiping, Xiang Kunsan

Abstract excerpt

BACKGROUND AND OBJECTIVE: Mutations of mitochondrial DNA are associated with diabetes mellitus (DM). The present case-control study aimed to investigate the mutations of mitochondrial DNA in DM patients of Chinese Han ethnicity. METHODS AND RESULTS: A total of 770 DM patients and 309 healthy control individuals were enrolled. The mitochondrial DNA was extracted from blood cells and analyzed by the polymerase...

Topics

Adult
Aged
Asian People
Case-Control Studies
DNA, Mitochondrial
Diabetes Mellitus, Type 2
Female
Humans
Male
Middle Aged
Point Mutation
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
Polymorphism, Single Nucleotide
Prevalence

Source

Open in PubMed

Identifiers

PMID: 24055484
DOI: 10.1016/j.gene.2013.09.019

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