Article
Novel mutations of mitochondrial DNA associated with type 2 diabetes in Chinese Han population.
The Tohoku journal of experimental medicine - 1 Aug 2008
Liao Wen-Qiang, Pang Yan, Yu Chang-An, Wen Jian-Yan, Zhang Yi-Guan, Li Xiao-Hui
Abstract excerpt
Mitochondrial single nucleotide polymorphisms (mtSNPs) have been reported to associate with type-2 diabetes mellitus (T2DM), but mtSNPs appear to be considerably different among different populations and regions. To determine mtSNPs in Chinese Han patients with T2DM, the entire sequences of the mitochondrial genomes from 72 T2DM Chinese (59 +/- 4 years) and 50 age-matched healthy subjects (controls) in Chongqing...
Topics
- Asian People
- Blood Glucose
- Body Mass Index
- China
- DNA Primers
- DNA, Mitochondrial
- Diabetes Mellitus, Type 2
- Glycated Hemoglobin
- Humans
- Lipids
- Middle Aged
