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Mitochondrial DNA Mutations Associated with Type 2 Diabetes Mellitus in Chinese Uyghur Population.

Scientific reports - 5 Dec 2017

Jiang Wenxi, Li Ronghui, Zhang Yongbiao, Wang Panpan, Wu Tingting, Lin Jinming, Yu Jun, Gu Mingliang

Abstract excerpt

A hospital-based case-control study was conducted to investigate potential association between mitochondrial DNA and Type 2 diabetes mellitus (T2DM) in Chinese Uyghur population. We sequenced mitochondrial DNA from 210 Uyghur individuals including 88 T2DM patients and 122 controls. Using haplogroup classification and association test, we found that haplogroup H (odds ratio [OR] = 1.40; 95% confidence interval...

Topics

Asian People
Case-Control Studies
China
DNA, Mitochondrial
Diabetes Mellitus, Type 2
Haplotypes
Humans
Mitochondria
Mitochondrial Proteins
Mutation
Prevalence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Ribosomal, 16S

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Open in PubMed Open full text

Identifiers

PMID: 29208909
DOI: 10.1038/s41598-017-17086-7
PMCID: PMC5717000

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