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[Study on the mitochondrial DNA mutations in familial diabetes mellitus in Chinese population].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Feb 2009

Wang Sui-jun, Wu Song-hua, Zheng Tai-shan, Wang Ling, Lu Hui-juan, Xiang Kun-san

Abstract excerpt

OBJECTIVE: To assess the prevalence of mutations or variants of the mitochondrial DNA (mtDNA) in familial diabetes mellitus in Chinese population, and to explore the relationship between mtDNA mutations or variants and diabetes. METHODS: Seven hundred and seventy randomly selected, unrelated probands of diabetes pedigrees and 309 controls over 60 years of age with normal glucose tolerance were recruited. PCR-RFLP...

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Identifiers

PMID: 19199242
DOI: 10.3760/cma.j.issn.1003-9406.2009.01.002

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