[Study on the mitochondrial DNA mutations in patients with early-onset diabetes mellitus].

Abstract excerpt

OBJECTIVE: To investigate the prevalence of mitochondrial DNA (mtDNA) mutations in patients with early-onset diabetes in Tianjin, and to explore the relationship between mtDNA mutations and diabetes. METHODS: 348 non-related patients whose age at onset of diabetes was less than 45 years were randomly recruited, and 207 non-related and non-diabetic subjects were enrolled as controls. All their clinical and...

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