Article
Differential interaction of the Pafah1b alpha subunits with the Reelin transducer Dab1.
Brain research - 24 Apr 2009
Zhang Guangcheng, Assadi Amir H, Roceri Mila, Clark Gary D, D'Arcangelo Gabriella
Abstract excerpt
The Reelin signaling pathway controls radial neuronal migration and maturation in the developing brain. The platelet activating factor (PAF) acetyl hydrolase 1b (Pafah1b) complex is also involved in multiple aspects of brain development. We previously showed that the Reelin pathway and the Pafah1b complex interact genetically and biochemically. Lis1, the regulatory subunit of Pafah1b interacts with phosphoDab1,...
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