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Article

Pafah1b2 mutations suppress the development of hydrocephalus in compound Pafah1b1; Reln and Pafah1b1; Dab1 mutant mice.

Neuroscience letters - 4 Jul 2008

Assadi Amir H, Zhang Guangcheng, McNeil Robert, Clark Gary D, D'Arcangelo Gabriella

Abstract excerpt

Reelin, an extracellular protein that signals through the Dab1 adapter protein, and Lis1 regulate neuronal migration and cellular layer formation in the brain. Loss of Reelin and reduction in Lis1 activity in mice or humans results in the disorganization of cortical structures. Lis1, the product of the Pafah1b1 gene associates with Alpha1 (the product of the Pafah1b3 gene) and Alpha2 (the product of the Pafah1b2...

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Identifiers

PMID: 18514414
DOI: 10.1016/j.neulet.2008.04.096
PMCID: PMC2680094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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