Article
The impact of copy number variation on local gene expression in mouse hematopoietic stem and progenitor cells.
Nature genetics - 1 Apr 2009
Cahan Patrick, Li Yedda, Izumi Masayo, Graubert Timothy A
Abstract excerpt
The extent to which differences in germline DNA copy number contribute to natural phenotypic variation is unknown. We analyzed the copy number content of the mouse genome to sub-10-kb resolution. We identified over 1,300 copy number variant regions (CNVRs), most of which are <10 kb in length, are found in more than one strain, and, in total, span 3.2% (85 Mb) of the genome. To assess the potential functional...
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