Article
Elusive copy number variation in the mouse genome.
PloS one - 21 Sept 2010
Agam Avigail, Yalcin Binnaz, Bhomra Amarjit, Cubin Matthew, Webber Caleb, Holmes Christopher, Flint Jonathan, Mott Richard
Abstract excerpt
BACKGROUND: Array comparative genomic hybridization (aCGH) to detect copy number variants (CNVs) in mammalian genomes has led to a growing awareness of the potential importance of this category of sequence variation as a cause of phenotypic variation. Yet there are large discrepancies between studies, so that the extent of the genome affected by CNVs is unknown. We combined molecular and aCGH analyses of CNVs in...
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