AI Analysis of a Copy Number Variant Database Identifies a Genetic Factor for a Murine Model of the Metabolic Syndrome

Abstract excerpt

Copy number variants (CNVs) are a major source of genetic diversity and could contain some of the missing heritability for mouse models of human disease. However, mouse CNVs have not been comprehensively characterized because they are difficult to resolve in repeat-rich, segmentally duplicated or reference sequence-absent regions of the genome. Here we analyzed long range sequence (LRS) data for 40 inbred mouse st...

Topics

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• Gene Dosage
• Mice, Inbred A
• Mice, Inbred AKR
• Mice, Inbred C3H
• Mice, Inbred CBA
• Mice, Inbred NOD
• Mice, Inbred NZB
• Nucleic Acid Hybridization

Identifiers and source

Literature Corpus work

0bb29697-3c6f-583b-8ef4-27da13ed6671

DOI

10.64898/2026.08.05.743102