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Article

Segmental copy number variation shapes tissue transcriptomes.

Nature genetics - 1 Apr 2009

Henrichsen Charlotte N, Vinckenbosch Nicolas, Zöllner Sebastian, Chaignat Evelyne, Pradervand Sylvain, Schütz Frédéric, Ruedi Manuel, Kaessmann Henrik, Reymond Alexandre

Abstract excerpt

Copy number variation (CNV) is a key source of genetic diversity, but a comprehensive understanding of its phenotypic effect is only beginning to emerge. We have generated a CNV map in wild mice and classical inbred strains. Genome-wide expression data from six major organs show not only that expression of genes within CNVs tend to correlate with copy number changes, but also that CNVs influence the expression of...

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PMID: 19270705
DOI: 10.1038/ng.345

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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