Article
Mouse segmental duplication and copy number variation.
Nature genetics - 1 Jul 2008
She Xinwei, Cheng Ze, Zöllner Sebastian, Church Deanna M, Eichler Evan E
Abstract excerpt
Detailed analyses of the clone-based genome assembly reveal that the recent duplication content of mouse (4.94%) is now comparable to that of human (5.5%), in contrast to previous estimates from the whole-genome shotgun sequence assembly. However, the architecture of mouse and human genomes differs markedly: most mouse duplications are organized into discrete clusters of tandem duplications that show depletion of...
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