Article
DinB upregulation is the sole role of the SOS response in stress-induced mutagenesis in Escherichia coli.
Genetics - 1 May 2009
Galhardo Rodrigo S, Do Robert, Yamada Masami, Friedberg Errol C, Hastings P J, Nohmi Takehiko, Rosenberg Susan M
Abstract excerpt
Stress-induced mutagenesis is a collection of mechanisms observed in bacterial, yeast, and human cells in which adverse conditions provoke mutagenesis, often under the control of stress responses. Control of mutagenesis by stress responses may accelerate evolution specifically when cells are maladapted to their environments, i.e., are stressed. It is therefore important to understand how stress responses increase...
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