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Article

Elevated expression of DNA polymerase II increases spontaneous mutagenesis in Escherichia coli.

Mutation research - 1 Dec 2007

Al Mamun Abu Amar M

Abstract excerpt

Escherichia coli DNA polymerase II (Pol-II), encoded by the SOS-regulated polB gene, belongs to the highly conserved group B (alpha-like) family of "high-fidelity" DNA polymerases. Elevated expression of polB gene was recently shown to result in a significant elevation of translesion DNA synthesis at 3, N(4)-ethenocytosine lesion with concomitant increase in mutagenesis. Here, I show that elevated expression of...

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Identifiers

PMID: 17586534
DOI: 10.1016/j.mrfmmm.2007.05.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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