Article
Isolation of SOS constitutive mutants of Escherichia coli.
Journal of bacteriology - 1 Nov 2004
O'Reilly Erin K, Kreuzer Kenneth N
Abstract excerpt
The bacterial SOS regulon is strongly induced in response to DNA damage from exogenous agents such as UV radiation and nalidixic acid. However, certain mutants with defects in DNA replication, recombination, or repair exhibit a partially constitutive SOS response. These mutants presumably suffer frequent replication fork failure, or perhaps they have difficulty rescuing forks that failed due to endogenous sources...
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