Article
Difference between age-related macular degeneration and polypoidal choroidal vasculopathy in the hereditary contribution of the A69S variant of the age-related maculopathy susceptibility 2 gene (ARMS2).
Molecular vision - 1 Jan 2011
Yanagisawa Suiho, Kondo Naoshi, Miki Akiko, Matsumiya Wataru, Kusuhara Sentaro, Tsukahara Yasutomo, Honda Shigeru, Negi Akira
Abstract excerpt
PURPOSE: To investigate whether the A69S variant of the age-related maculopathy susceptibility 2 gene (ARMS2) has a different hereditary contribution in neovascular age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV). METHODS: We initially conducted a comparative genetic analysis of neovascular AMD and PCV, genotyping the ARMS2 A69S variant in 181 subjects with neovascular AMD, 198...
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