Article
Immunohistochemical analysis of ZAP-70 expression in chronic lymphocytic leukemia.
Journal of molecular histology - 1 Feb 2009
Korać Petra, Ajduković Radmila, Kardum Paro Mirjana Mariana, Jaksić Branimir, Dominis Mara
Abstract excerpt
This paper shows a protocol for the detection of ZAP-70 expression in B-CLL (B cell chronic lymphocytic leukemia) tumor cells by common immunohistochemical methods. The study was conducted on bone marrow trephine biopsies from 62 B-CLL patients at the time of diagnosis. Immunohistochemical reactions based on peroxidase and alkaline phosphatase reactions were used, as well as double immunofluorescent labeling for...
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