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Article

Apolipoprotein E e4 allele is associated with more rapid motor decline in older persons.

Alzheimer disease and associated disorders - 1 Jan 2000

Buchman Aron S, Boyle Patricia A, Wilson Robert S, Beck Todd L, Kelly Jeremiah F, Bennett David A

Abstract excerpt

We tested the hypothesis that apolipoprotein E allele status predicts the rate of motor decline in the elderly. Eight hundred seventy-six older participants without dementia underwent baseline and annual motor testing for up to 10 years. In a generalized estimating equation controlling for age, sex, and education, motor function declined by about 0.03 U/y. The presence of epsilon4 allele was associated with a...

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Identifiers

PMID: 19266700
DOI: 10.1097/wad.0b013e31818877b5
PMCID: PMC2662708

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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