Article
Apolipoprotein E epsilon4 and change in cognitive functioning in community-dwelling older adults.
Journal of geriatric psychiatry and neurology - 1 Dec 2005
Swan Gary E, Lessov-Schlaggar Christina N, Carmelli Dorit, Schellenberg Gerard D, La Rue Asenath
Abstract excerpt
The relationship between apolipoprotein E (APOE) epsilon4 and change in cognition was examined in older men (n = 247; age = 75.0 +/- 3.5 years) and women (n = 79; age = 70.8 +/- 4.9 years) free of history of stroke. Participants were examined again 4.0 +/- 0.5 years later. Exclusion criteria were (1) initial scores on the Mini-Mental State Examination of 23 or less or (2) the presence of the APOE 2/4 genotype....
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