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Article

Parallel RNAi screens across different cell lines identify generic and cell type-specific regulators of actin organization and cell morphology.

Genome biology - 1 Jan 2009

Liu Tao, Sims David, Baum Buzz

Abstract excerpt

BACKGROUND: In recent years RNAi screening has proven a powerful tool for dissecting gene functions in animal cells in culture. However, to date, most RNAi screens have been performed in a single cell line, and results then extrapolated across cell types and systems. RESULTS: Here, to dissect generic and cell type-specific mechanisms underlying cell morphology, we have performed identical kinome RNAi screens in...

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Identifiers

PMID: 19265526
DOI: 10.1186/gb-2009-10-3-r26
PMCID: PMC2690997

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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