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Article

Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration.

BMC biology - 11 Aug 2011

Bai Siau Wei, Herrera-Abreu Maria Teresa, Rohn Jennifer L, Racine Victor, Tajadura Virginia, Suryavanshi Narendra, Bechtel Stephanie, Wiemann Stefan, Baum Buzz, Ridley Anne J

Abstract excerpt

BACKGROUND: Cell migration is essential during development and in human disease progression including cancer. Most cell migration studies concentrate on known or predicted components of migration pathways. RESULTS: Here we use data from a genome-wide RNAi morphology screen in Drosophila melanogaster cells together with bioinformatics to identify 26 new regulators of morphology and cytoskeletal organization in...

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Identifiers

PMID: 21834987
DOI: 10.1186/1741-7007-9-54
PMCID: PMC3201212

Genes

ARC
FMNL3
LIMD1
ZRANB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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