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Article

Regulation of Drosophila brain development and organ growth by the Minibrain/Rala signaling network.

G3 (Bethesda, Md.) - 6 Nov 2024

Brown Melissa, Sciascia Erika, Ning Ken, Adam Wesam, Veraksa Alexey

Abstract excerpt

The human dual specificity tyrosine phosphorylation regulated kinase 1A (DYRK1A) is implicated in the pathology of Down syndrome, microcephaly, and cancer; however the exact mechanism through which it functions is unknown. Here, we have studied the role of the Drosophila ortholog of DYRK1A, Minibrain (Mnb), in brain development and organ growth. The neuroblasts (neural stem cells) that eventually give rise to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 39271109
DOI: 10.1093/g3journal/jkae219
PMCID: PMC11540318

Genes

DYRK1A
RALBP1
REPS1
REPS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Regulation of Drosophila brain development and organ growth by the Minibrain/Rala signaling network.PMID 39271109Read ↗

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