Article
The A563T variation of the renal epithelial calcium channel TRPV5 among African Americans enhances calcium influx.
American journal of physiology. Renal physiology - 1 May 2009
Na Tao, Zhang Wei, Jiang Yi, Liang Youyou, Ma He-Ping, Warnock David G, Peng Ji-Bin
Abstract excerpt
The transient receptor potential cation channel, subfamily V, member 5 (TRPV5) gene, which encodes the Ca(2+) channel in the apical membrane of distal convoluted tubule and connecting tubule of the kidney, exhibits an unusually high frequency of nonsynonymous single nucleotide polymorphisms (SNPs) among African Americans. To assess the functional impacts of the nonsynonymous SNP variations in TRPV5, these...
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