Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Single Nucleotide Polymorphism (rs4236480) in TRPV5 Calcium Channel Gene Is Associated with Stone Multiplicity in Calcium Nephrolithiasis Patients.

Mediators of inflammation - 1 Jan 2015

Khaleel Anas, Wu Mei-Shin, Wong Henry Sung-Ching, Hsu Yu-Wen, Chou Yii-Her, Chen Hsiang-Yin

Abstract excerpt

Nephrolithiasis is characterized by calcification of stones in the kidneys from an unknown cause. Animal models demonstrated the functional roles of the transient receptor potential vanilloid member 5 (TRPV5) gene in calcium renal reabsorption and hypercalciuria. Therefore, TRPV5 was suggested to be involved in calcium homeostasis. However, whether genetic polymorphisms of TRPV5 are associated with kidney stone...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Kidney Stones and Urolithiasis Treatments

Share to Magnesium in Health and Disease

Share to Nephrolithiasis

Share to Polymorphism, Single Nucleotide

Share to TRPV Cation Channels

Source

Open in PubMed Open full text

Identifiers

PMID: 26089600
DOI: 10.1155/2015/375427
PMCID: PMC4452106

Genes

TRPV5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Single Nucleotide Polymorphism (rs4236480) in TRPV5 Calcium Channel Gene Is Associated with Stone Multiplicity in Calcium Nephrolithiasis Patients.PMID 26089600Read ↗

Association of TRPV5, CASR, and CALCR genetic variants with kidney stone disease susceptibility in Egyptians through main effects and gene-gene interactions.Semantic proximity Read ↗

TRPV5 gene polymorphisms in renal hypercalciuria.Semantic proximity Read ↗

A genetic polymorphism (rs17251221) in the calcium-sensing receptor gene (CASR) is associated with stone multiplicity in calcium nephrolithiasis.Semantic proximity Read ↗

TRPV5: a Ca(2+) channel for the fine-tuning of Ca(2+) reabsorption.Semantic proximity Read ↗

The L530R variation associated with recurrent kidney stones impairs the structure and function of TRPV5.Semantic proximity Read ↗

Decreased calcium permeability caused by biallelic TRPV5 mutation leads to autosomal recessive renal calcium-wasting hypercalciuria.Semantic proximity Read ↗

Genetics and calcium nephrolithiasis.Semantic proximity Read ↗

Common and rare variants associated with kidney stones and biochemical traits.Semantic proximity Read ↗

Association of single nucleotide genetic polymorphisms of vitamin D receptor and calcium-sensitive receptor with calcium-containing kidney stones in Chinese Dai populations: a prospective multi-center study.Semantic proximity Read ↗

Calcium-sensing receptor gene polymorphism (rs7652589) is associated with calcium nephrolithiasis in the population of Yi nationality in Southwestern China.Semantic proximity Read ↗

Association Study of Reported Significant Loci at 5q35.3, 7p14.3, 13q14.1 and 16p12.3 with Urolithiasis in Chinese Han Ethnicity.Semantic proximity Read ↗

The A563T variation of the renal epithelial calcium channel TRPV5 among African Americans enhances calcium influx.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.