Article
TRPV5 gene polymorphisms in renal hypercalciuria.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jun 2009
Renkema Kirsten Y, Lee Kyupil, Topala Catalin N, Goossens Monique, Houillier Pascal, Bindels René J, Hoenderop Joost G
Abstract excerpt
BACKGROUND: Kidney stone formation is a major socioeconomic problem in humans, involving pain, recurrent treatment and renal insufficiency. As most renal precipitates contain calcium as a major component, hypercalciuria is the main risk factor for renal stone formation. Different forms of hypercalciuria can be classified, which primarily arise from defects in the main organs involved in calcium homeostasis. A...
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