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Article

Differential ACE expression among tissues in allele-specific Wistar rat lines.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Mar 2009

Kamilic Jelena, Lely A Titia, van Goor Harry, Buikema Hendrik, Tent Hilde, Navis Gerjan J, Korstanje Ron

Abstract excerpt

In humans, the insertion/deletion polymorphism in the angiotensin converting enzyme (ACE) gene accounts for half of the variance in plasma ACE activity. The deletion allele is associated with high plasma ACE activity, cardiovascular disease, and renal disease. In rat, a similar association is found between the B and L alleles of a microsatellite marker in the ACE gene. We identified the B/L variation in the...

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PMID: 19255705
DOI: 10.1007/s00335-009-9173-x

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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