Article
Angiotensin I-converting enzyme modulates neutral endopeptidase activity in the rat.
Hypertension (Dallas, Tex. : 1979) - 1 Sept 2001
Oliveri C, Ocaranza M P, Campos X, Lavandero S, Jalil J E
Abstract excerpt
Angiotensin I is a substrate for both ACE and for neutral endopeptidase 24.11 (NEP). We hypothesized that high ACE expression is related to low NEP activity. Accordingly, circulating and tissue NEP and ACE activities were measured by fluorometry in homozygous rats (F(0) and F(2)) for the Lewis mi...
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