Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Angiotensin mutant mice: a focus on the brain renin-angiotensin system.

Neuropeptides - 1 Jan 2000

Morimoto Satoshi, Sigmund Curt D

Abstract excerpt

With advances in genetic manipulation and molecular biological and physiological techniques, the mouse has become the animal model of choice for studying the genetic basis of human diseases. The two most commonly used methods for analyzing the function of a gene in vivo, overexpression (transgenic mouse) and deletion (knockout mouse), have been extremely useful in establishing the importance of genes in genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensins
Share to Brain
Share to Mice

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Knockout

Share to Mice, Transgenic

Share to Mutation

Share to Renin-Angiotensin System

Source

Identifiers

PMID: 12359509
DOI: 10.1054/npep.2002.0894

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Angiotensin mutant mice: a focus on the brain renin-angiotensin system.PMID 12359509Read ↗

Transgenic mice as a tool to study the renin-angiotensin system.Semantic proximity Read ↗

[Functional role of angiotensin II predicted from the phenotypes of transgenic and knockout mice].Semantic proximity Read ↗

Renin–angiotensin system research: from molecules to the whole bodySemantic proximity Read ↗

A genetic approach for studying the physiology of the type 1A (AT1A) angiotensin receptor.Semantic proximity Read ↗

Increased Susceptibility of Mice Lacking Renin-b to Angiotensin II-Induced Organ Damage.Semantic proximity Read ↗

Gain-of-function mutant of angiotensin II receptor, type 1A, causes hypertension and cardiovascular fibrosis in mice.Semantic proximity Read ↗

New insights into the role of angiotensin-converting enzyme obtained from the analysis of genetically modified mice.Semantic proximity Read ↗

Synthesis and secretion of renin in mice with induced genetic mutations.Semantic proximity Read ↗

Physiological characterization of the hypertensive transgenic rat TGR(mREN2)27.Semantic proximity Read ↗

Blood pressures and cardiovascular homeostasis in mice having reduced or absent angiotensin-converting enzyme gene function.Semantic proximity Read ↗

Rediscovering ACE: novel insights into the many roles of the angiotensin-converting enzyme.Semantic proximity Read ↗

Functional expression of the human angiotensinogen gene in transgenic mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.