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Article

Unique splicing pattern of the TCF7L2 gene in human pancreatic islets.

Diabetologia - 1 May 2009

Osmark P, Hansson O, Jonsson A, Rönn T, Groop L, Renström E

Abstract excerpt

AIMS/HYPOTHESIS: Intronic variation in the TCF7L2 gene exhibits the strongest association to type 2 diabetes observed to date, but the mechanism whereby this genetic variation translates into altered biological function is largely unknown. A possible explanation is a genotype-dependent difference in the complex splicing pattern; however, this has not previously been characterised in pancreatic or insulin target...

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PMID: 19247628
DOI: 10.1007/s00125-009-1293-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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