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Article

The role of transcription factor 7‐like 2 in metabolic disorders

4 Dec 2020

Abstract excerpt

Transcription factor 7-like 2 (TCF7L2), a member of the T cell factor/lymphoid enhancer factor family, generally forms a complex with β-catenin to regulate the downstream target genes as an effector of the canonical Wnt signalling pathway. TCF7L2 plays a vital role in various biological processes and functions in many organs and tissues, including the liver, islet and adipose tissues. Further, TCF7L2...

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PMID: 33615650
DOI: 10.1111/obr.13166

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