Article
Functional Fc Gamma Receptor Gene Polymorphisms and Long-Term Kidney Allograft Survival.
Frontiers in immunology - 1 Jan 2021
Wahrmann Markus, Döhler Bernd, Arnold Marie-Luise, Scherer Sabine, Mayer Katharina A, Haindl Susanne, Haslacher Helmuth, Böhmig Georg A, Süsal Caner
Abstract excerpt
The functional Fc gamma receptor (FcγR) IIIA polymorphism FCGR3A-V/F158 was earlier suggested to determine the potential of donor-specific HLA antibodies to trigger microcirculation inflammation, a key lesion of antibody-mediated renal allograft rejection. Associations with long-term transplant outcomes, however, have not been evaluated to date. To clarify the impact of FCGR3A-V/F158 polymorphism on kidney...
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