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Article

Association of complement 5 genetic polymorphism with renal allograft outcomes in Korea.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Oct 2011

Jeong Jong Cheol, Hwang Young-Hwan, Kim Hyosang, Ro Han, Park Hayne Cho, Kim Yoon Jung, Kim Myung-Gyu, Ha Jongwon, Park Myoung Hee, Chae Dong Wan, Ahn Curie, Yang Jaeseok

Abstract excerpt

BACKGROUND: Complements play important roles in both rejection and ischemia-reperfusion injury after transplantation. Complement 5 (C5) is a pivotal complement, which initiates the assembly of the membrane attack complex, and mediates chemotaxis of various immune cells. We investigated the impacts of genetic variations in C5 and its receptor (C5aR) of both recipients and donors on renal allograft outcomes....

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Identifiers

PMID: 21393613
DOI: 10.1093/ndt/gfr025

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